Vascular Closure Device

David Colangione, MD

Content Contributor

Evolution of Vascular Closure Device

The benefits of needle sticks versus large incisions include shorter operations, shorter hospital stays, less pain, and fewer bleeding risks. Unfortunately, it does not avoid all complications. The vascular access-site, where the needle punctures the artery, is the main focus of these complications which can include things like bleeding, arterial wall ballooning (pseudoaneurysm), and separation of the layers of the arterial wall (dissection).

Historically, manual compression over the needle stick site has been the gold standard. It requires reversing or stopping anticoagulation, a prolonged bed rest, prolonged time to discharge, and can be uncomfortable for patients. Therefore, vascular closure devices have been developed as specific technology to improve on these limitations. These were introduced in the 1990’s and have several categories based on how they work. Examples are injecting pro-clotting agents, plugs, suture devices, or even clips.

Technology Spotlight

Abbott PerClose Proglide System

PerClose Proglide system is a vascular closure device that avoids an open incision and dissection down to the artery. It falls in the category of suture mediated percutaneous closure devices. The device uses a suture (polypropylene monofilament) with a preformed knot that is advanced down to the arterial wall and approximates the edges of the hole in the artery(arteriotomy), allowing for hemostasis and primary healing while providing reinforcement. It can be used for large-bore vessel closures and multiple devices can be deployed depending on the arteriotomy size.

Its advantages to the gold standard of manual pressure are improved patient comfort, shorter time to hemostasis, earlier post-procedural ambulation, earlier discharge, and less time required from hospital staff.