Negative pressure wound therapy (NPWT) is a method of soft-tissue injury treatment in which an impervious dressing is applied...
Irrigation and Debridement
Evolution of Irrigation and Debridement

Operative irrigation and debridement is the gold standard surgical procedure by which open fractures are initially managed. While timing for definitive osseous fixation varies depending on fracture severity and location, it is widely accepted that time to operative debridement should be no more than 6-8 hours. Effective operative debridement includes removal of foreign bodies, copious irrigation of the injury site, extension of soft tissue injury to fully visualize the field of injury, possible local infiltration of antibiotic, and primary or delayed soft-tissue closure.