Nerves are specialized bundles of tissue that transmit signals throughout the body. Nerve injury is a relatively common condition that can occur from different types of damage to the nerve. Nerves can be cut by sharp objects. They may also be damaged by pressure or stretch that may result from fractures, dislocation, crush injuries, or other traumatic injuries.
Nerve injury can be devastating and result in partial or complete paralysis of important muscle groups. The degree of injury and the potential for recovery without surgery depends on the degree of tissue and the specific parts of the nerve that are injured. When surgical repair is necessary, the timing of surgery will depend on the type and degree of nerve injury. Regardless of whether nerves are allowed to recover naturally or are repaired surgically, it often takes months to years to recover function.
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Avance nerve allograft (AxoGen) is a human nerve allograft that is processed to remove cells while preserving the connective tissue structure. The tissue structure of human nerve is retained throughout processing, so recovering nerve is able to regenerate across existing structural elements. Avance allografts are used in nerve repair to bridge a gap when direct repair is not possible, or when there is tension when the cut ends are approximated. They are available in various lengths and diameters to conform to various gap lengths and injured nerve sizes.